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Pathogenesis. Leptospira spp. penetrate the intact mucous membranes or abraded skin, enter the bloodstream and spread to all parts of the body, including the cerebrospinal fluid (CSF) and eyes. Liver damage is subcellular and may lead to jaundice.
Pathogenesis. Leptospira enters the host through mucosa and broken skin, resulting in bacteremia. The spirochetes multiply in organs, most commonly the ...
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Infection by pathogenic strains of Leptospira commonly occurs through direct contact with infected animal urine or indirectly through contaminated water. Almost ...
Leptospira interrogans requires heme oxygenase for disease pathogenesis. Microbes Infect. 11, 311–314 (2009). Article CAS PubMed Google Scholar. Lo, M. et al ...
Apr 24, 2003 · As with most other pathogenic bacteria, L. interrogans possesses several genes related to the attachment and invasion of eukaryotic cells (mce, ...
Prior to 1989, the genus Leptospira was divided into two species: Leptospira interrogans (pathogenic strains) and Leptospira biflexa (saprophytic strains).
This species is pathogenic to some wild and domestic animals, including pet dogs. It can also spread to humans through abrasions on the skin, where infection ...
Pathogenic leptospires attain their virulence due to the presence of various proteins (especially outer membrane proteins), allowing them to transmit and cause ...
ABSTRACTLeptospirosis is a life-threatening and emerging zoonotic disease with a worldwide annual occurrence of more than 1 million cases.
Jul 4, 2018 · Leptospira interrogans is a pathogenic, spirochetal bacterium that is responsible for leptospirosis, an emerging worldwide zoonosis.
